Generation of Novel Detection and Treatment strategies for prostate cancer
This project involves the production of antibodies to biomarkers of prostate cancer, their use in
developing an early-stage diagnostic test and , ultimately, use of an antibody-based bifunctional approach to image and treat prostate cancer. We have a team of researchers in DCU and our affiliates linked to international collaborators, working on prostate cancer. We envisage use of a microfluidics-based biochip as the detection platform and linking this to early diagnosis and disease management.
Barcodes ‘check out’ prostate cancer. S. Hearty, P. Leonard and R. O’Kennedy. (2010)
Nature Nanotechnology, 5, 9-10.
Overcoming antibody expression and screening limitations by smart design: applications to PSA
immunoassay development. C. Hayes C, P. Leonard P, R. O'Kennedy R. Protein Expr Purif. 2012
May;83(1):84-91. Epub Mar 13.